Thursday, September 24, 2009

ICAAC: Nutritional Supplement Slows CD4 Loss in Untreated HIV

www.HopeandHelpCenter.org

September 24, 2009
ICAAC: Nutritional Supplement Slows CD4 Loss in Untreated HIV

A nutritional supplement developed by Danone—a French food company known in the United States as Dannon and most recognized for its dairy products—might slow the decline of CD4 cells in people living with HIV not yet receiving antiretroviral (ARV) therapy, according to new study results reported September 14 at the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco.

According to a news release from Nutricia, Danone’s parent company, the results of the 52-week study testing the nutritional compound currently known as NR100157 exceeded the company’s expectations and is likely to be developed further.

NR100157 contains five major groups of compounds: probiotic oligosaccharides, N-acetylcysteine (NAC), bovine colostrums, long chain polyunsaturated fatty acids and micronutrients.

In 2007, Nutricia started the international BITE study—a clinical trial comparing NR100157 with placebo in 340 people living with HIV not yet on ARV therapy in Australia, Argentina, Brazil, Italy, the Netherlands, Thailand, the United States or the United Kingdom. About half of the 340 patients enrolled received the NR100157, which is produced as a powder and dissolved in liquid or mixed in food.

About halfway through the study in 2008, a planned interim analysis involving 52 weeks of follow-up was conducted by the researchers, including Pedro Cahn, MD, PhD, of the Buenos Aires University Medical School in Argentina, who presented the preliminary findings at ICAAC.
Twenty-five of the 168 study volunteers randomized to receive NR100157 dropped out of the study because they needed to begin ARV therapy.

In the placebo group, consisting of 172 study volunteers, 29 dropped out so that they could start ARV treatment. More than twice as many people living with HIV in the NR100157 group, compared with those in the placebo group, quit the study because of possible side effects, notably bloating and flatulence
.
Despite high rates of discontinuation during the first half of the two-year study, Cahn and his colleagues noted encouraging differences between the two groups. In the NR100157 group, the average CD4 decline during the 52-week follow-up period was 28 cells, compared with 68 cells in the placebo group—a difference of 40 cells that just managed to qualify as statistically significant.
Based on these results, an independent Data Safety Monitoring Board (DSMB) recommended that the study be stopped prematurely. What remains unclear, however, is why a study of this nature would be stopped when there is little evidence of harm, limited commercial access to the tested agent and a desire for long-term follow-up data from studies of nutritional supplements.

Search: NR100157, supplement, propbiotic, CD4 cells, Danone, Dannon, BITE, Nutricia, ICAAC

Wednesday, September 23, 2009

Nationwide Public Health Alert Issued Concerning Life-Threatening Risk Posed by Cocaine Laced with Veterinary Anti-Parasite Drug

www.HopeandHelpCenter.org

Media Contact: SAMHSA Press
Telephone: 240-276-2130

Nationwide Public Health Alert Issued Concerning Life-Threatening Risk Posed by Cocaine Laced with Veterinary Anti-Parasite Drug
The Substance Abuse and Mental Health Services Administration (SAMHSA) is alerting medical professionals, substance abuse treatment centers and other public health authorities about the risk that substantial levels of cocaine may be adulterated with levamisole – a veterinary anti-parasitic drug. There have been approximately 20 confirmed or probable cases of agranulocytosis (a serious, sometimes fatal blood disorder), including two deaths, associated with cocaine adulterated with levamisole. The number of reported cases is expected to increase as information about cocaine adulterated with levamisole is disseminated.

“SAMHSA and other public health authorities are working together to inform everyone of this serious potential public health risk and what measures are being taken to address it,” said SAMHSA Acting Administrator Eric Broderick, D.D.S., MPH.

Levamisole is used in veterinary medicine and is currently approved for use in cattle, sheep and swine as an anti-parasitic agent. Although it was once used in human medicine in the past for treating autoimmune diseases and cancer, it is no longer an approved drug for human use.

Ingesting cocaine mixed with levamisole can seriously reduce a person's white blood cells, suppressing immune function and the body's ability to fight off even minor infections. People who snort, smoke, or inject crack or powder cocaine contaminated by levamisole can experience overwhelming, rapidly-developing, life threatening infections. Other serious side effects can also occur.

According to the Drug Enforcement Administration and State testing laboratories, the percentage of cocaine specimens containing levamisole has increased steadily since 2002, with levamisole now found in over 70 percent of the illicit cocaine analyzed in July. In addition, a recent analysis in Seattle, Washington found that almost 80 percent of the individuals who test positive for cocaine also test positive for levamisole.

According to the SAMHSA alert substance abuse treatment providers, clinicians, outreach workers, and individuals who abuse cocaine need to be aware of the following:

A dangerous substance, levamisole, is showing up with increasing frequency in illicit cocaine powder and crack cocaine. Levamisole can severely reduce the number of white blood cells, a problem called agranulocytosis. THIS IS A VERY SERIOUS ILLNESS THAT NEEDS TO BE TREATED AT A HOSPITAL. If you use cocaine, watch out for:

* high fever, chills, or weakness
* swollen glands
* painful sores (mouth, anal)
* any infection that won’t go away or gets worse very fast, including sore throat or mouth sores -skin infections, abscesses -thrush (white coating of the mouth, tongue, or throat) -pneumonia (fever, cough, shortness of breath).”

SAMHSA is working with the U.S. Centers for Disease Control and Prevention (CDC), the Drug Enforcement Administration, the Food and Drug Administration, the Office of National Drug Control Policy, and other federal and international organizations, as well as state agencies to monitor the levamisole issue. CDC will be publishing a case report analysis in the Morbidity and Mortality Weekly Report (MMWR) and will be working with state health departments to systematically collect information on cocaine-associated agranulocytosis cases. Information from this effort will be used to guide treatment and prevention initiatives to address this public health concern.

Individuals are encouraged to report suspected and confirmed cases of agranulocytosis that are associated with cocaine abuse to their respective state health departments. Cases can also be reported to local Poison Control Centers (1-800-222-1222), these centers may also provide assistance in clinical management and additional reporting.

For further medical/technical information, contact Nicholas Reuter, SAMHSA (Nicholas.reuter@samhsa.hhs.gov ).
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SAMHSA is a public health agency within the Department of Health and Human Services. The agency is responsible for improving the accountability, capacity and effectiveness of the nation's substance abuse prevention, addictions treatment, and mental health services delivery system.

www.SAMHSA.hhs.gov
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Wednesday, September 16, 2009

Health Policy Update - Missouri Foundation for Health

www.HopeandHelpCenter.org

Proposed Federal Medicaid Regulations: Impact on Missouri - Fact Sheet

The Centers for Medicare & Medicaid Services (CMS), the federal agency responsible for monitoring and regulating state Medicaid programs, have proposed seven regulatory changes that would reduce federal funding for the Medicaid program. In Missouri, these regulations would reduce federal funding by approximately $1.4 billion over the next 5 years.
Pay-for-Performance: Considerations for Implementation - Fact Sheet
To improve clinical outcomes and encourage patient-centered care, private and public health plans are offering financial incentives to providers through a model known as “Pay-for-performance”(P4P). Congress and many policy institutions have begun promoting “P4P” as a component to long-term quality improvement across the health care system. This fact sheet provides a definition and background of the term P4P. It also explains the many design features, implementation challenges and policy considerations associated with the model.

Long-Term Care: Issues and Policy Considerations - Fact Sheet
This fact sheet explores the current state of long-term care in the U.S. and identifies several public policy issues that must soon be addressed at both the state and national level.

Raising Medicaid Reimbursement to Increase Provider Participation - Fact Sheet
In most states, Medicaid physician reimbursements rates are lower than those for Medicare and private insurance. In 2003, Missouri Medicaid to Medicare fee index was 56 percent. Research indicates that raising reimbursement for Medicaid providers results in an increased number of Medicaid patients they treat. This fact sheet examines the issues related to reimbursement rates.

Supporting Private Insurance Through Premium Assistance - Fact Sheet
Premium assistance programs offer states the potential to cut the number of uninsured, to strengthen the system of employer-sponsored insurance, and to reduce federal and state expenditures for public insurance. This fact sheet examines the advantages and disadvantages associated with designing and implementing various types of premium assistance programs.


Primary Care Medical Homes: Policy Issues for Consideration - Fact Sheet
Policymakers across the country are pursuing initiatives to establish medical homes as a response to rising health care costs, gaps in preventative coverage, and poor management of chronic conditions. This fact sheet defines medical homes and explores policy options associated with their implementation.

SOURCE~ MISSOURI FOUNDATION FOR HEALTH
http://www.mffh.org/fact_sheets.html

Tuesday, September 15, 2009

Free HIV tests for Seniors- Sept 18th


www.hopeandhelpcenter.org

Are you sexually active and over 50? Have you been tested lately for HIV?

September 18th is the first National HIV/AIDS & Aging Awareness Day. St. Louis Effort for AIDS will be conducting free HIV tests from 10 a.m. - 3 p.m. for people over 50 (walk-ins welcomed).

http://theaidsinstitute.org/asp/ai_events.asp?ms=4&ss=55

For more information contact:

Cyrano Jones, Testing Coordinator
Saint Louis Effort for AIDS
1027 South Vandeventer Avenue - Suite 700
Saint Louis, Missouri 63110
(314) 333-6668-Direct (314) 645-6582-Fax
cjones@stlefa.org

Source_ http://www.sagemetrostl.org/

Grief Conference : Living with the Echoes of Grief Sept 26th

www.HopeandHelpCenter.org
Grief Conference : Living with the Echoes of Grief

The Greater St. Louis Hospice Organization

Saturday, Sept. 26

8:30 am - 12:30 pm

St. John's Mercy Medical Center

615 S. New Ballas Rd. 63141


636-733-7399

This program is open to anyone in the community who has suffered a loss. There is no charge for this seminar. Donations are accepted. Pre-registration required.

Thursday, September 10, 2009

Free Breast Cancer Screening Sept 16th

www.HopeandHelpCenter.org

There are still appointments open for the September 16, Mammography Screening. Attached you will find the flyer and contact information.

Breast Cancer Screening
Isaiah 58 Ministries

2149 S. Grand Blvd., 63104

9:00 am - 2:30 pm

Free mammograms and breast exams for women.
Appointments required - (314) 776-1410.

Tuesday, September 8, 2009

Risk Factors for Low Platelets in People With HIV

www.HopeandHelpCenter.org

September 8, 2009
Risk Factors for Low Platelets in People With HIV

Hepatitis C virus (HCV) infection, severe liver damage and uncontrolled HIV replication are all associated with a greater risk for low platelets in people with HIV,
according to a study published online September 3 in the Journal of Acquired Immune Deficiency Syndromes.

Thrombocytopenia, the technical term for too few platelets, was once quite common in people living with HIV. Having a low platelet count means that the blood has a harder time forming clots, which amplifies the chance of bruising and excessive bleeding—increasing the risk of stroke in severe cases. The incidence of thrombocytopenia since the introduction of potent three-drug combination HIV therapy is not well known, though it has dropped.

To determine the likelihood of developing thrombocytopenia, Kristen Marks, MD, MS, and her colleagues from Weill Cornell Medical College in New York City, compared 73 people with HIV who were diagnosed with thrombocytopenia with 73 people with HIV who did not have the condition.

The two groups were matched based on age, sex and other health factors, such as using drugs that can cause low platelet counts. The average age was 41; about half of the participants were female; and just over half had a CD4 count greater than 200. Marks and her colleagues found that HCV infection—particularly uncontrolled HCV infection and advanced liver disease—made someone far more likely to have thrombocytopenia. Interestingly, uncontrolled HIV infection was also highly associated with low platelets, regardless of a person’s CD4 count or previous AIDS diagnosis.

The authors conclude that people with HCV and HIV coinfection should be monitored carefully for low platelets, as even mild thrombocytopenia can result in internal bleeding. Thrombocytopenia should also be carefully considered when deciding whether to start interferon-based HCV treatment because that drug can contribute to low platelet counts. Marks’s team also comments that the majority of thrombocytopenia cases in people without HCV or liver damage are likely a result of uncontrolled HIV replication; the authors note that further research will be necessary to understand why this is the case.

Original Story: http://www.poz.com/rssredir/articles/hiv_thrombocytopenia_hcv_761_17223.shtml
Search: thormbocytopenia, platelets, bleeding, bruising, Kristen Marks, hepatitis C virus, HCV, liver damage

Monday, September 7, 2009

Suicide Prevention Training at St. Patrick Center 9-24-09

www.HopeandHelpCenter.org

3. Suicide Prevention Training at St. Patrick Center

September 24 9:00am – 11:00 am

Registration 8:30 – 9:00am Fee $15

Catholic Charities Conference Center
800 N. Tucker St. Louis
314-802-5413

Energy and Health Forum Sept 12

1. Energy and Health Forum

September 12 10:00am – 3:00pm

Wild Acres Park
2500 Ashby Rd.
Overland, 63114
314-446-4424

Sponsored by The Overland Business Association & Community Action Agency of St. Louis. There will be workshops on energy conservation, demonstrations on installing weatherizing materials, free home weatherization kits and more!

2. Understanding the Role Race Plays in St. Louis

September 9 3:00 – 4:30 pm
J.C. Penney Conference Center Room 126
Univ. of Missouri
1 University Blvd.

314-516-6392
Sponsored by Community Partnership Project at UM-St. Louis

A panel of nurses and doctors will speak on inequalities in the health care field and the effects of these differences.

3. Suicide Prevention Training at St. Patrick Center

September 24 9:00am – 11:00 am

Registration 8:30 – 9:00am Fee $15

Catholic Charities Conference Center
800 N. Tucker St. Louis
314-802-5413

Friday, September 4, 2009

Breast Cancer Screening (Isaiah 58 Ministries)

www.HopeandHelpCenter.org

Breast Cancer Screening
Isaiah 58 Ministries

2149 S. Grand Blvd., 63104
10:00 am - 2:30 pm
Free mammograms and breast exams for women.
Appointments required - (314) 776-1410.
http://hopeandhelpcenter.org/women.aspx

Upcoming HEALTH EVENTS- Sept 9th, 12th& 24th

www.HopeandHelpCenter.org
1. Energy and Health Forum
September 12 10:00am – 3:00pm

Wild Acres Park
2500 Ashby Rd.
Overland, 63114
314-446-4424

Sponsored by The Overland Business Association & Community Action Agency of St. Louis. There will be workshops on energy conservation, demonstrations on installing weatherizing materials, free home weatherization kits and more!


2. Understanding the Role Race Plays in St. Louis
September 9 3:00 – 4:30 pm


J.C. Penney Conference Center Room 126
Univ. of Missouri
1 University Blvd.
314-516-6392

Sponsored by Community Partnership Project at UM-St. Louis
A panel of nurses and doctors will speak on inequalities in the health care field and the effects of these differences.


3. Suicide Prevention Training at St. Patrick Center
September 24 9:00am – 11:00 am

Registration 8:30 – 9:00am Fee $15
Catholic Charities Conference Center
800 N. Tucker St. Louis
314-802-5413

Thanks and have a great day!

Peace

Alexa Previti
Gateway Vincentian Volunteer
St. John's Mercy Neighborhood Ministry
3660 Gravois Ave
Saint Louis, MO 63116
314-865-0927 ext 4 314-865-0679 (fax)
Alexa.Previti@Mercy.net
stjohnsmercy.org/services/neighborhoodministry